Chinese Journal of Oncology Prevention and Treatment ›› 2013, Vol. 5 ›› Issue (3): 239-242.doi: 10.3969/j.issn.1674-5671.2013.03.11
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Abstract: Objective To investigate whether the cellular immunity status of intracranial tumors correlates with their WHO classification. Methods In this retrospective analysis of 79 patients operated on for intracranial tumors between August 2010 and May 2013,flow cytometry was used to assess levels of various T cell populations in the tumor tissue,and the WHO classification of the tissue was determined by postoperative pathology.Possible correlations between T cell populations and WHO classification were investigated using Spearman′s rank correlation. Results In the final analysis of 57 patients, levels of T cells positive for CD3+,CD4+/CD8+,CD8+,CD16+ CD56+ and CD19+ did not correlate with WHO classification.However, the level of CD4+ T cells negatively correlated with WHO classification (P<0.05). Conclusions In intracranial tumors,cellular immunity status does not significantly correlate with WHO classification.
Key words: Intracranial neoplasms, Cellular immunity, WHO classification
DENG Teng,ZENG Xian-jie,XU Jian,MO Li-gen. Correlation between the cellular immunity status and WHO classification of intracranial tumors[J].Chinese Journal of Oncology Prevention and Treatment, 2013, 5(3): 239-242.
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